Endocrine Abstracts

The Nonclassical Congenital Adrenal Hyperplasia (NCCAH) is an autosomal recessive disorder. The importance of the diagnosis in fertile women relies in its therapeutic implications, genetic counseling and antenatal care during pregnancy. Diagnosis is established by the presence of basal 17-OH-progesterone (17-OHP) levels ≧6 ng/ml or stimulated after ACTH test ≧15 ng/ml. Basal values between 2-6 ng/ml or stimulated between 10–15 ng/ml would require further con...

A 49 years old male patient with 12 years history of poorly controlled type 2 diabetes mellitus on insulin therapy, complicated with neuropathy, nephropathy, retinopathy, peripheral arterial disease (right toe amputation), hypertension and dyslipidemia. He presented with upper extremities proximal muscle and upper back moderate pain that progressed to excruciating pain with restriction of motion, weakness, and stiffness of 3 days of evolution. He denied trauma, abnormal exerci...

Introduction: Protocols for identifing and managing hyperglycemia and diabetes in hospital are necessary. Glycemic goals in non critical inpatients are:140 mg/ml(preprandial) and 180(posprandial),oral antidiabetic drug(OADs) withdrawn, avoid hypoglycemias, basal/bolus insulin (nor sliding scale) and request glycosylated haemoglobin.Aims: To evaluate the implementation of a protocol for management of diabetes(PHD) during the years 2009 and 2010 in our Hos...

Introduction and objective: Neuroendocrine tumors (NETs) are relatively rare tumors. The majority are located in the gastrointestinal (GI) tract and bronchopulmonary system. The aim of this report is to study the characteristics of gastrointestinal NETs at diagnosis.Material and methods: Descriptive study about 18 patients diagnosed of gastrointestinal NETs during 1993–2011 in our hospital. Data regarding demographic, clinical, analytical, anatomopa...

Introduction and objective: Neuroendocrine tumors (NETs) are a rare kind of tumor that can have various locations. Pancreatic location is the most common after the gastrointestinal tract. The aim of this report is to study the characteristics of neuroendocrine tumors located in the pancreatic gland (pNETs) at diagnosis.Material and methods: Descriptive and retrospective study about 22 patients diagnosed of pNET during the period 1993–2010 in our hos...

Introduction: It has been previously described that prolactinomas may have a more aggressive behaviour in men than in women.Methods: We performed a retrospective study in 59 patients diagnosed of prolactinoma (19 men). The variables collected were: age at diagnosis, clinical presentation, tumor size and stage (Hardy classification) and treatment response. The results were compared between both genders.Results: Age at diagnosis was ...

Aim: Patients with malignant neuroendocrine tumors (mNETs) present frequently metastatic disease at diagnosis or during their follow-up. Hepatic transplant (HT) and radionuclide treatment have proved to be successful treatments. The aim of this report is to study the progression of the disease in patients with metastasic mNETs and HT.Patients and methods: Descriptive and retrospective study of patients diagnosed of metastasic mNETs and submitted to HT du...

Differentiated carcinoma of the thyroid (DCT) of follicular origin is the most frequent endocrine neoplasia and it usually has a good prognosis even in the disseminated disease, due to its slow growing pattern and low dissemination rate. The prevalence of metastasis described in the literature varies between 5 and more than 20%.Aims: To analyze the clinical–pathological data and their relation with survival of patients (pts) with metastatic DTC....

Introduction: Isolated ACTH failure is a rare disorder characterized by a secondary adrenal failure and a considerable deterioration of the general state. In adults the has been established related to cranial traumatism and to autoimmune hypophysitis (AH). It has been pointed out that the isolated failure of pituitary tropin in the context of a AH, could end with a global pituitary failure.Objective: Evaluation of the shortage of isolated ACTH as a way o...

Background: Obesity has been associated with low levels of 25-hydroxyvitamin D (25(OH)D). This could be explained by a low dietary intake, reduced sun exposure or less biodisponibility because of its arrest in the fat mass. The main objective is to study the prevalence of 25(OH)D deficiency in premenopausal obese women.Methods: Aleatory sample of 100 morbidly obese patients. Selection criteria were: women, premenopausal, Caucasian. Patient with diabetes ...